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Stromal cell-derived factor-1 is upregulated by dipeptidyl peptidase-4 inhibition and has protective roles in progressive diabetic nephropathy
Additionally, caution should be exercised in patients with a history of pancreatitis, gastroparesis, or hypersensitivity to any of the GLP-1 receptor agonist components
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The TRIUMPH clinical trial program is evaluating retatrutide for multiple indications beyond simple weight loss, including obesity with osteoarthritis, obesity with metabolic complications, type 2 diabetes, cardiovascular outcomes, obstructive sleep apnea, and metabolic dysfunction-associated steatohepatitis
Is tirzepatide dosed the same as semaglutide