much lower at community doses Vomiting up to 36% at high doses Diarrhea 23-26% Constipation 17-19% Fatigue 11-13% Pancreatitis risk trials flagged severe abdominal pain for discontinuation and evaluation Gallbladder issues rapid weight loss increases gallstone risk Thyroid C-cell tumors same boxed warning as semaglutide (animal studies) GI side effects were more intense than semaglutide in trial data due to the dual mechanism
Injections usually require a prescription, while oral supplements are often available over the counter
Losing 50 to 100 hairs per day during the exogen phase is normal
Targeting factor Xa and thrombin: impact on coagulation and beyond
Avoid rubbing, as this can irritate the skin
In this model, the Top represents the maximal response, the Baseline is the minimum response, the Bottom is the lowest value of the dose-response curve, LogAbsoluteIC50 is the logarithmic value of the IC, X is the independent variable (concentration), and HillSlope indicates the steepness of the curve