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The most clinically significant comparative finding came from the SURMOUNT-5 head-to-head trial in 2024, the first direct comparison between two FDA-approved weight loss medications

Dose escalation raises the price on most programs, so the $199 starting month is not the steady-state number once you reach a maintenance dose

Fluid timing : Distribute fluid intake throughout the day, with individualized recommendations regarding evening intake to balance hydration needs with potential nocturia

Sidney Barritt IV, MD, director of hepatology at UNC School of Medicine in Chapel Hill, North Carolina

PMID: 74 KhoiC

[DOI] [PubMed] [Google Scholar] 44.Kumar V., Gill K