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Symptoms of Appendicitis Its worth keeping in mind that the symptoms of appendicitis can mimic those of other digestive problems, and that it can quickly escalate into a medical emergency: the appendix can rupture very rapidly (48 to 72 hours) after the onset of symptoms

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Metformin is effective, but feared because of putative side effects

It's important to note that these side effects are typically mild and often resolve on their own

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