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Cost: prescription medications may carry substantially higher out-of-pocket costs, depending on the specific drug, pharmacy price, insurance coverage, and any manufacturer assistance program

Most GLP-1-related side effects can be avoided by slow titration and conservative dosing

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The SEMALEAN trial found lean mass declined then stabilised while handgrip strength improved by 4.5 kg and sarcopenic obesity prevalence fell from 49% to 33% over twelve months

Can the patient fill the prescription at their preferred pharmacy

Because of this, your clinician might suggest waiting before evaluating results, so the medication has time to reach its full effect