surmount-1 trial tirzepatide weight loss non-diabetic SURMOUNT-1: Adults achieve of 16% or more at 72 weeks with 💊 Could a new medication

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Semaglutidea GLP-1 receptor agonist originally approved for type 2 diabeteshas become a cornerstone of weight loss treatment, with clinical trials showing 15% average body weight reduction over 68 weeks

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[38] reported that the activation of InsR and IGF-1R induced the binding and phosphorylation of JAK1 and JAK2 proteins, thus promoting their activation in NIH3T3 fibroblasts

References Ristoff E, Augustson C, Geissler J, de Rijk T, Carlsson K, Luo JL, Andersson K, Weening RS, van Zwieten R, Larsson A, Roos D: A missense mutation in the heavy subunit of gamma-glutamylcysteine synthetase gene causes hemolytic anemia

Science 370 , 856860 (2020)