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Methylxanthine Derivatives Pharmacologic Effects Methylxanthines include caffeine, a potent respiratory stimulant, and theobromine, a recognized canine toxicant from chocolate and theophylline (Figure 20-6)

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Although the S Tyr1272 side chain was indeed closer to the mutant WD40 surface by 0.8 (Fig

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Nature 460 , 392395 (2009)

doi: 10.1042/EBC20200032 112 PengWXKoiralaPMoYY