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Conversely, total PYY concentrations have recently been found to be increased, both pre- and postprandially, in patients with Crohns disease affecting the small intestine

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In theory, neither the health professionals conducting the studies nor the patients participating in the trials know who is getting the active drug and who is getting the placebo

Conceio EM, Mitchell JE, Machado PPP, Vaz AR, Pinto-Bastos A, Ramalho S, et al

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PMID 40465419 "Identification of alexamorelin consumption biomarkers using human hepatocyte incubations and high-resolution mass spectrometry" (2025)