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Simultaneously, BPC-157 upregulates growth hormone receptors in tissue fibroblasts, enhances ERK1/2 signaling for cell proliferation, and activates the FAK-paxillin pathway for cellular adhesion and migration
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In addition, there is a hybrid receptor with components of the IR (one and one -chain) and the IGF-1R (one and one -chain), to which both insulin and IGF-1 can bind to, but with less affinity than that of their putative receptors [98100]
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