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Phentermine is meant for short-term use because the body develops a tolerance to it within a few weeks

Escobar-Morreale Cardiovascular Diabetology.2023;[Epub] CrossRef Early Gastrointestinal Neuropathy Assessed by Wireless Motility Capsules in Adolescents with Type 1 Diabetes Vinni Faber Rasmussen, Mathilde Thryse, Pll Karlsson, Esben Thyssen Vestergaard, Kurt Kristensen, Ann-Margrethe Rnholt Christensen, Jens Randel Nyengaard, Astrid Juhl Terkelsen, Christina Brock, Klaus Krogh Journal of Clinical Medicine.2023

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However, making very important lifestyle changes like eating a healthy diet and getting more physically active often are not enough to prevent regaining weight