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Genetic differences that affect drug processing abilities can determine the speed at which semaglutide is metabolized in the body which in turn influences its therapeutic effectiveness and safety profile

For each included study, we extracted HRs with corresponding 95% CIs for outcomes of interest: AUD diagnosis and alcohol-related hospitalization

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Although originally designed for scRNA-seq, RNA velocity has also been applied to snRNA-seq datasets, where studies demonstrate strong concordance between nucleus- and cell-derived velocity estimates in matched samples