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Lawley, J

TZP treatment was not associated with increased CV risk (72, 76)

Neurotoxicology and Teratology 32 :515-524

People with diabetic kidney disease (DKD) experienced side effects similar to those of people with T2D and/or cardiovascular disease

De la misma forma que con otros anticuerpos monoclonales quimricos, son frecuentes las reacciones infusionales, que se pueden manifestar con fiebre, cefalea, hipotensin, disnea y erupcin cutnea morbiliforme en las 24-48 h posteriores a la primera infusin del frmaco

Excessive release of glutamate and its binding with NMDA, -amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA), or kainite (KA) receptors promotes excitotoxicity cell injury with a consequent activation of many molecular pathways, resulting in intracellular calcium (Ca 2+ ) overload 90,91 , reactive oxygen species (ROS) production, mPT, and cell swelling with brain edema 92