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The procedure is generally well tolerated, with high patient satisfaction and a low incidence of mild, transient adverse side effects like erythema, edema, and sensory changes.44 Despite its success in treating localized adiposity, the application of cryolipolysis for lipedema remains under-investigated

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First, exendin-4 activated GLP-1R/cAMP/PKA pathway and attenuated endoplasmic reticulum stress in order to inhibit bone marrow-derived MSC apoptosis mediated by oxygen, glucose, and serum deprivation (57)