ATP: adenosyl triphosphate, B6: vitamin B6, B12: vitamin B12, BHMT: betaine homocysteine methyltransferase, CBS: cystathionine-?-synthase, DHF: dihydrofolate, DMG: dimethylglycine, dTMP: deoxythymidine monophosphate, dUMP: deoxyuridine monophosphate, Gly: glycine, Hcy: homocysteine, MAT: methionine adenosyltransferase, Met: methionine, MCM: L-methylmalonyl CoA mutase, MM-CoA: L-methylmalonyl CoA, MMA: methylmalonic acid, MS: methionine synthase, MTHFR: 5,10-methyltetrahydrofolate reductase, SAH: S-adenosyl homocysteine, SAHH: S-adenosyl homocysteine hydrolase, SAM: S-adenosyl methionine, Ser: serine, SHMT, serine hydroxymethyltransferase, THF: tetrahydrofolate, TS: thymidylate synthase
Gastroenterology 162 , 20042017.e2002 (2022)
B.MinnichV
Respiratory Issues : Although rare, some individuals may experience mild shortness of breath or wheezing
It is a systemic, inflammatory condition
The pause is therefore framed in research as protective and restorative , not as lost ground