All authors reviewed the final manuscript
The risk becomes relevant primarily in cases of severe or prolonged symptoms requiring medical intervention
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Although most of the time PWS patients did not show a promising post-surgical compliance, bariatric surgery is the only possibility for weight loss A study on 60 American patients with PWS showed after 5 years from surgery a weight loss of only 2.4%, significantly less than that observed in non-PWS subjects with obesity, however, as anticipated this data could be influenced by different types of surgery performed, some of which are now obsolete (54% biliopancreatic diversion, 29% gastric bypass, 18% bioenteric intragastric balloon, 5.4% jejunoileal bypass, 3.6% gastroplasty, 3.6% vertical banded gastroplasty, 1.8% silicone band gastroplasty, and 1.8% truncal vagotomy) and that many subjects, 49 PWS patients, were lost to follow-up [103]
