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The lipid radical reacts with molecular oxygen to form a lipid peroxyl radical, which can further propagate the chain reaction by abstracting hydrogen atoms from neighboring fatty acids, leading to a cascade of lipid peroxidation [9]

CircRREB1 mediates lipid metabolism related senescent phenotypes in chondrocytes through FASN post-translational modifications

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For these reasons, the peptide is commonly included in anti-aging skin products [10, 11]

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When the demand on GSH increases when more substrate is being conjugated, when the GPx reaction is running faster the cell pulls more heavily on GR and on the upstream synthesis machinery