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However, the authors note that substantial weight loss can be accompanied by reductions in lean body mass, underscoring the need for further research into dosing strategies and interventions that preserve muscle while promoting fat loss

Many people experience them most intensely at the start of treatment or after a dose increase, and then notice improvement as the body adjusts

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This is not a failure of willpower but rather reflects the medication's role in appetite regulation and the body's metabolic adaptation

Some people experience a brief weight plateau or small regain of 1-3 pounds during transition, which typically stabilizes within four to six weeks

Wegovy is specifically tested and approved for weight loss, while Ozempic is approved to treat type 2 diabetes