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We believe theres a really durable weight business, said Dudum, even if you think youre kind of in a draconian scenario of compounding GLP-1s not being there. But investors see the companys short-term prospects as tightly linked to the GLP-1 weight loss drugs that it began prescribing in May 2024

The key lesson from ACE-031 was that broad TGF-beta superfamily inhibition produces unacceptable off-target effects, particularly vascular toxicity

These therapies do not typically cause hypoglycemia on their own but may occur when used in combination with additional glycemic drugs

This guide explains what GLP-1 and GIP actually are, how they differ in function, why combining both creates additive benefits, and what this means for choosing between medications

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