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L.McMinimyR.Martnez-GonzlezB.et al (2021)

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Table 7: Mean Changes in Anthropometry and Cardiometabolic Parameters After 36-Week Open-Label Treatment Followed by Randomized Withdrawal (Study 4) in Patients with Obesity or Overweight Obstructive Sleep Apnea Studies in Adults with Obesity Overview of Study 5 and Study 6 The efficacy of ZEPBOUND for moderate to severe obstructive sleep apnea (OSA) (apnea-hypopnea index [AHI] 15) in patients with obesity (BMI 30 kg/m2) was evaluated in a master protocol clinical trial (NCT05412004) that included two randomized, double-blind, placebo-controlled trials (Study 5 and Study 6) of 52 weeks duration

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The procedure was performed five times for each sample

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Most investigators specialized in endocrinology and internal medicine, with others specializing in family medicine, psychiatry and clinical psychology

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Patients seeking smoking cessation support should contact their GP or NHS Stop Smoking Service for appropriate, licensed treatments with proven efficacy

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The agouti gene product inhibits lipolysis in human adipocytes via a Ca2+-dependent mechanism

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