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Author contributions YuZ and XQ designed the study

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Yaker and colleagues 18,19 generated a liver-specific IGF-I deficient mouse (LID mouse) under the control of albumin promoter and clarified the role of IGF-I produced by liver on the skeleton

This work was supported by the Fundamental Research Program of Shanxi Province (202403021212266) and the Changzhi Medical College Research Initiation Funds for PhD (BS202317)

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