It should not be framed as a general fat-loss injection or a bodybuilding peptide
The National Anti-Doping Agency in India issued a 2 year suspension to a weightlifter who tested positive for SERMS
6 In contrast, BRP operates through a non-incretin pathway, targeting the hypothalamus to regulate energy balance independently of GLP-1 receptor activation
Bioavailability is affected by a number of other factors, which are particular to any one individual
The maximum dose tested in Phase 2 was 12mg once weekly, where 24.2% body weight loss was recorded at 48 weeks (Jastreboff et al., NEJM 2023)
While innovation in medicine is important, it should proceed via clinical trials, not by leapfrogging around regulations and experimenting on those who trust us