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Both are building redundancy into their supply chains to prevent bottlenecks like those that plagued early launches

Novo Nordisks Wegovy pill was approved in late December 2025, marking the first true no-injection GLP-1 era

This extra receptor interaction enhances glucagon production, leading to the breakdown of stored fats and glycogen, thereby increasing basal metabolism for more consistent fat loss

The comparison is useful, but it has limits

Clinical trial starting doses The landmark phase 2 trial published in the New England Journal of Medicine randomized 338 participants across multiple dose groups

Theres also dysesthesia, a burning, prickling skin sensation that hit roughly one in eight high-dose patients in the obesity trial and up to one in five in the knee trial, something earlier GLP-1s mostly dont cause