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Fat browning refers to the high plasticity of white fat cells, which can be transformed into beige fat cells with many similar morphological and functional characteristics to brown fat cells under the stimulation of exercise, cold exposure, adrenergic receptor stimulation, and other factors [83]

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LDLR / global knockout mice were housed in the same environment as C57BL/6J mice, with free access to water and a high-cholesterol diet (HCD

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