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GIP receptor agonism Retatrutide activates glucose-dependent insulinotropic polypeptide (GIP) hormone receptors to enhance insulin secretion and glucose reuptake in cells and slow down gastric emptying

2 Introduction/background: history of incretin mimetics medications GIP was the first incretin isolated and characterized in the 1970s though most modern therapies focus on GLP-1 [17]

Isolation and characterization of inulin with a high degree of polymerization from roots of Stevia rebaudiana (Bert.) Bertoni

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