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J Biol Chem 2000 ;275:1699-707 74 -Tein I ea Pediatr Res 1993;34:281-7 75 -Marzo A ea
The most frequent gastrointestinal side effects include: Nausea and vomiting : Very common, typically most pronounced during dose escalation Diarrhoea : Common to very common, though usually mild to moderate Constipation : Can occur due to delayed gastric emptying and reduced gut motility Abdominal pain and discomfort : Common Dyspepsia and gastro-oesophageal reflux : May worsen in susceptible individuals Other important adverse effects include: Gallbladder disorders : Cholelithiasis and cholecystitis have been reported, particularly with weight loss Dehydration and acute kidney injury : May occur secondary to severe gastrointestinal symptoms Hypoglycaemia : Risk increases when used with insulin or sulfonylureas, which may require dose adjustment Current limited evidence does not suggest an increased risk of inflammatory bowel disease (IBD) flares with GLP-1 agonists, though more data are needed
Some of the side effects of glutathione The use of glutathione should be under expert guidance
Learn about health risks and recommended limits.
Sustained caloric restriction, even when clinically intended, can lead to micronutrient insufficiencies that compound fatigue, cognitive fog, and muscle loss side effects that are often misattributed to the medication itself
Black Box Warning : GLP-1 receptor agonists carry a warning regarding an increased risk of thyroid C-cell tumors
