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Conclusion: Cinchonine, a potential oral small-molecule GLP-1R agonist, could reduce blood glucose and ameliorate NASH, providing a strategy for developing small-molecule GLP-1R agonists
David Systrom regarding blood shunting in ME/CFS
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Liver issues are uncommon on GLP-1s, but contact your healthcare provider if you notice persistent fatigue beyond typical medication adjustment, upper right abdominal discomfort, dark urine or pale stools, yellowing of the skin or eyes, or nausea that worsens rather than improves over time