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doi: 10.1016/s1369-5274(00)00162-4 29 BanksMGrahamDJansenMGotodaTCodaSdi PietroMet al

Coordination Chemistry of Nitrosyls and Its Biochemical Implications

(2023) 15:e40948

Primary mechanisms studied: VEGFR2 upregulation, Akt-eNOS axis activation, ERK1/2 and FAK-paxillin signaling, NF-kB downregulation, growth hormone receptor upregulation, Egr1 activation [1] [4] [5]

Both forms can be highly effectivebut they tend to excel in different therapeutic contexts