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Some larger Felidae species, such as the tiger ( Panthera tigris ), the lion ( Panthera leo ), and the Javan leopard ( Panthera pardus melas ), have experienced significant population declines in recent decades (IUCN, 2022)

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U-100 insulin syringe

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The safety status of LAB, the ability of some strains to survive passage through the gastrointestinal tract (GIT) [10], and the capacity of some species to remain viable in the GIT for a period of time render food-grade LAB ideal vehicles with which to deliver and even produce therapeutic molecules in situ at the GIT mucosa [11]