can b12 injections cause migraines I've had a migraine since Sept 4th. I took a injection that day (prescribed by my doctor) so I'm wondering if it's related or coincidence. I'm scared to take another one Vitamin B12 Deficiency and Migraine

You can, but results will be negligible

Sikiric et al., 2013

Always inject close to the affected area for maximum benefit

For suspected macro-B12, precipitation with PEG is the test most often reached for, though it is nonspecific and can remove B12 that is fully available to cells, so direct measurement of the binding proteins, haptocorrin and transcobalamin, may be more informative when it is available

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If we are lucky and our mother had a good supply of B12, we would be born with a store, but this eventually runs out or stops being accessible for many reasons