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B12 requires active folate (5-methyltetrahydrofolate) to function properly in the methionine synthase reaction, but folate levels are often low in people with MTHFR variants

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Peptides like Dihexa and Selank can improve cognitive function, making them useful for treating conditions like Alzheimers disease and other forms of cognitive decline

Improves long and short-term memory: By enhancing synaptic plasticity and connectivity, Dihexa supports the neural architecture underlying memory encoding and retrieval

Because the body cannot produce methionine on its own, it must be obtained through dietary sources or supplementation when clinically indicated

Guidelines for the diagnosis and treatment of cobalamin and folate disorders British Society for Haematology