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Malignant Triton tumors

These shifts one enhancing lipid transport, the other limiting the detoxification of lipid peroxidation presumably create cellular conditions that favor oxidative damage and ferroptosis

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Analysis of diabetic kidneys from global ANGPTL4 mutant mice and podocyte- and tubule-specific ANGPTL4 mutant mice showed suppressed levels of renal fibrosis, proteinuria, proinflammatory cytokines, and mesenchymal activation in tubules and endothelial cells, suggesting that renal ANGPTL4 is associated with fibrosis, proteinuria, inflammation, and mesenchymal activation in diabetic kidneys (Srivastava et al., 2024)