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group A (control), group B (alloxan 150mg/kg intraperitoneally) and group C (alloxan 150mg/kg intraperitoneally + L-carnitine 500mg/kg orally for 21 days)

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Patients with certain genetic profiles may respond better to tirzepatide (a dual GLP-1/GIP agonist) than semaglutide alone

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It appears to be even less effective in normal-weight individuals, even when combined with exercise