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Conversely, venglustat, a glucosylceramide synthase inhibitor, failed to show any clinical benefit over placebo in GBA1-related PD in part 2 of a recent phase 2 trial [126], after having demonstrated favourable safety, tolerability, and target engagement in the cerebrospinal fluid (CSF) in part 1 of the same trial [127]

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These statistics apply to the broader supplement market but highlight risks in unregulated peptide sourcing

I do day/night 500mcg totaling 1mg 3 times per week