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Deficiency in B12 can lead to demyelination, resulting in neurological symptoms such as numbness, tingling, impaired coordination, and cognitive decline

While this is beneficial for tissue repair, people with conditions where angiogenesis is undesirable should discuss this with their healthcare provider

Injection site reactions, flushing, and transient hyperglycemia are reported but rare

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Aerobic eukaryotes have developed antioxidant defense mechanisms which act by mitigating damaging effects of excessive ROS production, hence under physiological conditions there is a dynamic balance between the ROS generation and elimination [22]

Bear MF, Connors BW, and Paradisio MA