Common gastrointestinal side effects include nausea, vomiting, diarrhoea, constipation, and abdominal pain, which may overlap with Crohn's symptoms
The injections, Tirzepatide and Semaglutide, are pharmaceutical treatments administered via subcutaneous injection to aid in weight loss
Compounded medications contain the same active pharmaceutical ingredient as the FDA-approved brand-name drugs (Wegovy, Ozempic, Zepbound, Mounjaro), but the compounded versions themselves are not FDA-approved as finished products and have not been individually evaluated by the FDA for safety, efficacy, or quality
Individuals with a history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN 2), as well as those with type 1 diabetes, diabetic ketoacidosis, severe pancreatic disease, uncontrolled gastric disease, or Individuals with a semaglutide GLP-1 allergy should avoid Ozempic
Marso SP, Daniels GH, Brown-Frandsen K, et al, for the LEADER Steering Committee on behalf of the LEADER Trial Investigators
However, if the dose is too high, it may lead to under-eating, leading to nutritional deficiencies and hyperglycemia