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claims that peptides dramatically compress this timeline in humans are not supported by clinical evidence

Notably, these extracts (especially leaf extracts) showed enhanced effects in strengthening intracellular antioxidant defences like catalase, superoxide dismutase, and glutathione to lower lipid peroxidation products and reduce prominent pro-inflammatory markers such as tumor necrosis factor-, interleukin (1L)-, IL-6, monocyte chemoattractant protein-1 and nitric oxide synthase

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This risk is generally higher in individuals with darker skin tones, as their melanin-rich skin is more reactive to heat

J Helminthol 90:129138