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5,6 Mosaicplasty, typically osteochondral autologous transplantation (OATs), is an open procedure where osteochondral plugs are harvested from non-weight bearing areas and transferred into the defect

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Doctors commonly prescribe it for neuropathy, especially in diabetic patients who experience tingling, numbness, or burning sensations

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Non-coding RNAs (ncRNAs) regulation, DNA methylation, RNA methylation, and histone modifications are seen as the main mechanisms of epigenetic regulations