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Waiting until breastfeeding cessation allows access to full-strength semaglutide injection or tirzepatide therapy without lactation safety concerns, often with better treatment outcomes because caloric restriction is not balanced against milk production needs

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Moreover, peptides in GLP-1 drugs are derived from living cells through recombinant DNA technology, which makes their manufacturing process more complex and expensive than traditional pills

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Lipophilic compounds can become trapped in the mucus rather than diffusing through to the epithelium, reducing absorption efficiency

A review of serious adverse events linked with glp-1 agonists in type 2 diabetes mellitus and obesity treatment