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The PD-L1/PD-1 interaction inhibits critical T cell signaling pathways (e.g., PI3K/AKT/mTOR), ultimately leading to exhaustion and apoptosis of the T cells, creating an immunosuppressive shield for tumors (88, 89)

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Suggested Use: Adults: 1 capsule, 1 to 3 times daily or as directed by a healthcare professional

A doctor may sometimes recommend combining oral support, topical therapy, and selected in-clinic procedures depending on clinical findings and patient goals

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