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SGLT-2 inhibitor and GLP-1 receptor agonist treatment for patients with nonalcoholic fatty liver disease and type 2 diabetes mellitus: is their combination the optimal treatment option

The distinction matters because the treatment approach differs completely

They offer essential nutrients

There was no increased rate of adverse effects leading to discontinuation of treatment in GLP-1RA users compared with nonGLP-1RA users (112)

Obviously, cancer of any type is not something that you want to deal with

A peptide like retatrutide, with its triple agonist activity (GLP-1, GIP, glucagon), can deliver powerful effects, yet this very potency requires that the dosing remain measured and carefully managed