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Description

In the HLA-B27 rat model of colitis, administration of teduglutide at the dose of 50 g/kg/day decreased histological lesions in small and large intestine, decreased expression of the inflammatory cytokines, such as IFN- and TNF-, and improved stool consistency in comparison with control group (Alavi et al

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Firstly, the proposed treatment was nontoxic and well tolerated

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When the First GLP-1 Agonist Received FDA Approval Exenatide became the first GLP-1 receptor agonist approved by the FDA in 2005 under the brand name Byetta

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CJC-1295 No DAC (Mod GRF 1-29) is a 29-amino-acid GHRH analog with four substitutions (D-Ala, Gln, Ala, Leu) for enhanced stability and receptor affinity

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