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doi: 10.1007/s13730-020-00512-7 13 Al BishawiAAbdel HadiHElmekatyEAl SamawiMNairAAbou KamarMet al

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Thus, GSH plays the role of a mediator in crucial cellular processes, such as cell cycle progression and programmed cell death ( The GSH itself is created from amino acids, including glutamate, L-cysteine, and glycine, through two ATP-dependent enzymatic reactions mediated by -glutamylcysteine synthetase (-ECS or also known as GSH1) and GSH synthetase (GS or also named GSH2) ( Figure 1 )

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