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Third, irradiation of endothelial cells alters the expression of intercellular cell adhesion molecule-1 (ICAM-1), vascular cell adhesion molecule-1 (VCAM-1), and Platelet endothelial cell adhesion molecule-1 (PECAM-1) also known as cluster of differentiation 31 (CD31), increases vascular permeability and leads to intestinal mucosal oedema 42

These studies indicate that leptin is therapeutically useful for the long-term treatment of insulin-deficient diabetes and diet-induced obesity, serving as a newer adjunct therapy for treating type1 and type2 diabetes

In addition, Brazilian research published in the Journal of Clinical Endocrinology & Metabolism does not show a clear link between Ozempic and breast cancer

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