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The PLAG1-GDH1 axis promotes anoikis resistance and tumor metastasis through CamKK2-AMPK signaling in LKB1-deficient lung cancer

Split dosing (smaller doses twice daily, morning and bedtime) theoretically stimulates multiple daily pulses

Sep 10 2020;383(11):1050-1056

Recommendation : Vitamin B-12 (as cyanocobalamin) 2,500mcg or more, can be combined with Folic Acid 400 to 800 mcg, dissolved slowly under the tongue, the morning or early afternoon, once daily, or as directed by your healthcare provider

After treatment, you can immediately resume your daily activities