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Characterising how specific amino acid changes in variant receptors alter binding affinity, Gs coupling efficiency, cAMP signalling, and MITF activation in response to MC1R agonist stimulation

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Inhibition of oxidative stress and the NF-B pathway by a vitamin E derivative: Pharmacological Approach against Parkinsons Disease

It's a compound with a well-characterized mechanism, positive animal data, and a cluster of smaller human studies pointing in the right direction

Of course, the potential side effects do exist and sound uncomfortablenausea, stomach pain, and constipation, to name just a few