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Mitochondrial dysfunction and cell growth disorder by GSTP silencing, and their restoration by ROS elimination In addition to increasing the ROS level, comparative proteomics also suggested mitochondrial dysfunction due to GSTP-silencing
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In the second Nurses Health Study II, the risk of breast cancer was significantly higher in younger women with 20 or more years of cumulative shift work, reflecting the exposure of younger individuals (HR=2.15, 95% CI: 1.23, 3.73
10.1289/ehp.94102s1085
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The resulting decrease in thyroid hormones impacts cells throughout the body, causing symptoms such as: Fatigue Weight gain Headaches and migraines Thinning or dry hair, nails, and skin Feeling cold all the time Irregular periods Puffiness or fluid retention Fertility problems Slow digestion and constipation Brain fog Depression Aching muscles and joints Loss of muscle strength and tone These symptoms may be vague early on, but the inflammation can result in an enlarged thyroid (goiter) and thyroid nodules over time
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