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doi: 10.5772/intechopen.76558 4 DemainALVaishnavP

Se evalu la farmacocintica de semaglutida en pacientes con insuficiencia heptica leve, moderada o grave en comparacin con personas con funcin heptica normal en un estudio en el que se administraba semaglutida una vez al da durante 10 das consecutivos

Cardiovascular mortality Compared with placebo, tirzepatide and the GLP-1RA class significantly reduced the risk of CV mortality (HR 0.77, 95% CI 0.660.90 and HR 0.87, 95% CI 0.810.92, respectively).- Heterogeneity across studies was low (Q = 11.76, p = 0.227