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In the 12-week human pilot study, thigh muscle size decreased, but handgrip and knee extension strength did not worsen

According to recent research published in medical journals, retatrutide achieved up to 24.2% mean weight loss after 48 weeks in individuals with obesity

As with other agents in the incretin receptor agonist class, the most frequently reported side effects of retatrutide in the Phase 2 clinical trial were gastrointestinal in nature

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Analysis of 18 samples on an LC-QTOF platform detected 15,377 peaks, with 2,766 metabolites annotated