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Our research provided direct evidence that GSDMD-mediated pyroptosis regulated perfusion recovery after HLI by affecting the production and secretion of cytokines, aiming to identify novel targets in the pyroptosis process after ischemic injury for the prevention and treatment of PVD

The American Diabetes Association estimates 20 to 50% of patients on systemic corticosteroids develop new-onset hyperglycemia, and up to 2% develop new-onset type 2 diabetes after long courses