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Study endpoints include epithelial-barrier function, tight-junction protein expression, inflammatory signaling, and mucosal tissue remodeling in models of intestinal inflammation, increased permeability, and chemically induced gastrointestinal injury

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GLP-1/exendin-4 induces -cell proliferation via the epidermal growth factor receptor

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A short course is often practical, and long-term use may require a lower maintenance dose with tapering under medical supervision